FAQ
1.What is your products range?
A: Peptides pharmaceuticals, Cosmetic peptide, Custom peptide, OEM Service for Personalized cancer neoantigen peptide vaccine etc.
2.How to confirm the product quality before placing orders?
A: Offering you our products specification standard. If you have special requirements, we may customize it according to your requirement until to your approval.
3.What is the payment term?
A: T/T, Western Union, Paypal, Money Gram etc.
4.What is your package?
A: Powder: PE bag, aluminium foil bag, glass bottle or PTFE bottle for inner packing.
Liquid: Glass bottle or PTFE bottle for inner packing
Bulk order: Fiber drum or steel drum.
5.What is your delivery term?
A: FOB, CIF, etc. You can choose the one which is the most convenient or cost effective for you.
6.How to delivery by express?
A: Parcel will be shipped by DHL, Fedex, TNT, EMS, ePacket and USA Domestic mixed shipping and so on.
7.Is there a discount?
A: Yes, for larger quantity, we always support with better price.
8.What's your MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.
Taiwan Oyi Peptide Co.Ltd. established in 2014, is a subsidiary company of Nanjing Spec-Chem Group. It is a professional peptide high-tech company integrating research and development, production and service.
Oyi Peptide has a 900m2 GMP plant workshop for polypeptide Purification equipment, freeze-drying and packaging in-line; it has established a strict quality management system, and built a GMP workshop in accordance with international standards, and a high-quality quality management team, SOP operation are strictly followed to bring out the company's effective quality assurance system.
It has many sets of large Solid-phase and Liquid-phase Reactors,six sets of preparative HPLC system over 150mm, more than 20 sets of analytical HPLC system and many sets of Agilent HPLC (High Performance Liquid Chromatography, American waters HPLC, mass spectrometer.
Top-notch peptide synthesis and purification technology, built a fast and high-throughput peptide synthesis platform, several hundred thousand of peptides banks.
It can synthesize 2-120 amino acids, purity of 99% cosmetic beauty peptide, annual production capacity (lyophilized powder) more than 100 kg.
The company can satisfy the needs from different customers, provide customized services for universities and pharmaceutical research institutions, and can provide a variety of peptide modification services for customers.
Such as Isotope labeling (2H, 15N, 13C), PEG modification, disulfide bonds, KLH, BSA, OVA peptide-coupled modification; Modification of peptide such as acetylation, amination, methylation, biotin labeling, fluorescence, etc. The beauty peptides developed and produced by the company include: anti-wrinkle and anti-aging, whitening and Anti-Spot, tighten and repairing, soothing and anti-allergic, promoting hair growth, promoting hair turning black, removing eye bags and dark circles, breast enhancement and slimming and etc.
The core team of Oyi Peptide is composed of senior experts and professors with more than 20 years of experience in the R&D and production of peptides. It has first-class liquid phase synthesis and solid phase synthesis technology, as well as mature and leading separation and purification technology, we are able to provide customers with various peptide-related technical services and products such as peptides technology development, drug R&D, custom synthesis, beauty polypeptides etc.
With independent intellectual property rights--The patented technology of polypeptide separation and purification, improves the market competitiveness of products greatly, Becomes a high-quality partner of many pharmaceutical factories, research institutes, universities and multinational companies in the daily chemical industry.
Pure Peptide,Pure Life.
This is the corporate philosophy and sacred mission practiced of our Oyi Peptide, and also the goal of our contribution to society.
In accordance with the spirit of Honest and pragmatic, pioneering and innovative, improving constantly, leading Leon Biotech's higher and farther development.
Hard-earned, serve customers with quality, head-up, Create future with technology.
Chemical synthesis Methods of peptides:
Solid-phase synthesis:In 1963, R.B.Merrifield established a solid phase synthesis method by which the C-terminal of amino acids was fixed on insoluble resin, and then the amino group is deprotected and reacted with the carbonyl group of the next N-protected amino acid. This cycle is repeated to form the desired peptide chain. After all reactions are complete, the synthesised peptide is cleaved from the resin. In the solid-phase method, the purification can be achieved by simply washing the resin after each step of the reaction, which overcomes the difficulty of purifying the products in each step of the classical liquid phase synthesis method, and lays a foundation for the automatic synthesis of peptides. Therefore,Merifield won the 1984 Nobel Prize in Chemistry.
After continuous development, the solid phase method mainly refers to Fmoc method.
Advantages: used in the synthesis of medium and long peptides, good purity of crude peptides
Disadvantages: high cost, large solvent ,relatively small quantity
Liquid phase synthesis method: BOC and Z protection methods are mainly used in short peptides synthesis
Advantages: relatively low cost, small solvent , relatively big quantity
Disadvantages: long production cycle, poor purity of crude peptides
Leon's team developed a new approach to the continuous solution synthesis of many peptides, which is as efficient as the solid-phase synthesis method, and at the same time solves the problems of cumbersome operation and poor purity of crude products.
Mg to kg liquid and solid phase synthesis reactor
Purification of peptides:
At present, reversed-phase high performance liquid chromatography are used as mainly purification methods of peptides . The commonly mobile phase system is water-acetonitrile or water-methanol, (TFA) as ion pair reagent, to separate peptides with appropriate gradient elution.
Most peptides are purified in TFA system, so the most peptides are TFA salt. Secondly, pharmaceutical peptides generally are acetate and hydrochloride, and some pharmaceutical peptides have special salt forms. ion exchange and HPLC method are mainly methods to change salt form , and commonly G25 column(dextran gel column) is used to remove salt
Mg to kg reversed-phase high performance liquid purification equipment
Lyophilization of peptides: peptides are purified by HPLC, and most of organic solvents and water are removed by rotary evaporator, and then peptides are lyophilized by lyophilizer.
Storage of peptides:
Most peptides remain active for several years if kept below -10ºC conditions, preferably -20ºC.
When using frozen products, the bottles or tubes should be brought to room temperature in a dry box with desiccant before opening the lid.
Once opened, it should be quickly weighed and closed immediately to avoid deliquescence, especially hydrophilic peptides.
Mg to kg vacuum freeze-drying equipments
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